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Biblioteca (s) : |
INIA Tacuarembó. |
Fecha : |
09/04/2021 |
Actualizado : |
09/04/2021 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
QUEIROZ, C.R.R.; MACHADO, M.; BROMBERGER, C.R; OLIVEIRA-FILHO, J.P.; BORGES, A.S.; SOTO-BLANCO, B.; BORGES, J.R.J.; CÂMARA, A.C.L.; CASTRO, M.B.D. |
Afiliación : |
CINTIA REGINA RÊGO QUEIROZ, Veterinary Pathology Laboratory, University of Brasília, Campus Darcy Ribeiro, Brasília, Brazil; MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CRISTIANA RAACH BROMBERGER, Department of Veterinary Clinical Science, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil; JOSE PAES OLIVEIRA-FILHO, Department of Veterinary Clinical Science, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil; ALEXANDRE SECORUN BORGES, 3 Department of Veterinary Clinical Science, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil; BENITO SOTO-BLANCO, Department of Veterinary Clinics and Surgery, Veterinary College, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; JOSÉ RENATO JUNQUEIRA BORGES, 5 College of Agronomy and Veterinary Medicine, Large Animal Veterinary Teaching Hospital, University of Brasília, Brasília, Brazil; ANTÔNIO CARLOS LOPES CÂMARA, College of Agronomy and Veterinary Medicine, Large Animal Veterinary Teaching Hospital, University of Brasília, Brasília, Brazil; MÁRCIO BOTELHO DE CASTRO, Veterinary Pathology Laboratory, University of Brasília, Campus Darcy Ribeiro, Brasília, Brazil. |
Título : |
Case report: A possible case of congenital Erythropoietic Porphyria in a gir calf: a clinical, pathological, and molecular approach. |
Fecha de publicación : |
2021 |
Fuente / Imprenta : |
Frontiers in Veterinary Science, 12 March 2021, Volume 8, Article number 632762. OPEN ACCESS. Doi: https://doi.org/10.3389/fvets.2021.632762 |
DOI : |
10.3389/fvets.2021.632762 |
Idioma : |
Inglés |
Notas : |
Article history: Received: 24 November 2020; Accepted: 05 February 2021; Published: 12 March 2021. |
Contenido : |
Congenital erythropoietic porphyria (CEP) is a rare hereditary autosomal recessive disease which has never been reported in Zebu cattle. A 3-day-old Gir calf showed teeth discoloration, fever, dehydration, and dyspnea. The main gross findings were pink-colored teeth, red-brown periosteum and bone marrow, and a fluorescent bright pink coloration of the bone marrow and articular surfaces under ultraviolet light. Aggregates of periodic acid-Schiff (PAS)-stained porphyrin pigments were evident in the lungs, kidneys, and the liver. An intron 8 single-nucleotide polymorphism (SNP) in both the Gir calf and control animals, along with the absence of the uroporphyrin III synthetase (UROS) gene mutation, was observed. Most SNPs were located in the intron regions of the UROS gene without relevance for CEP. A continuous loss of genetic variability and an increase in inbreeding in some herds may be related to CEP in Gir cattle, one of the most prominent Zebu breeds worldwide. In summary, this study describes a presumptive case of CEP in a Gir calf based on clinical and pathological findings. A definitive diagnosis
would require the measurement of porphyrin levels in blood, urine, or tissues or the identification of UROS gene defects. |
Palabras claves : |
CATTLE; PINK TEETH; PORPHYRIN; UROPORPHYRIN; VETERINARY; ZEBU. |
Asunto categoría : |
L70 Ciencias veterinarias e higiene - Aspectos generales |
URL : |
https://www.frontiersin.org/articles/10.3389/fvets.2021.632762/pdf
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Marc : |
LEADER 02328naa a2200313 a 4500 001 1061968 005 2021-04-09 008 2021 bl uuuu u00u1 u #d 024 7 $a10.3389/fvets.2021.632762$2DOI 100 1 $aQUEIROZ, C.R.R. 245 $aCase report$bA possible case of congenital Erythropoietic Porphyria in a gir calf: a clinical, pathological, and molecular approach.$h[electronic resource] 260 $c2021 500 $aArticle history: Received: 24 November 2020; Accepted: 05 February 2021; Published: 12 March 2021. 520 $aCongenital erythropoietic porphyria (CEP) is a rare hereditary autosomal recessive disease which has never been reported in Zebu cattle. A 3-day-old Gir calf showed teeth discoloration, fever, dehydration, and dyspnea. The main gross findings were pink-colored teeth, red-brown periosteum and bone marrow, and a fluorescent bright pink coloration of the bone marrow and articular surfaces under ultraviolet light. Aggregates of periodic acid-Schiff (PAS)-stained porphyrin pigments were evident in the lungs, kidneys, and the liver. An intron 8 single-nucleotide polymorphism (SNP) in both the Gir calf and control animals, along with the absence of the uroporphyrin III synthetase (UROS) gene mutation, was observed. Most SNPs were located in the intron regions of the UROS gene without relevance for CEP. A continuous loss of genetic variability and an increase in inbreeding in some herds may be related to CEP in Gir cattle, one of the most prominent Zebu breeds worldwide. In summary, this study describes a presumptive case of CEP in a Gir calf based on clinical and pathological findings. A definitive diagnosis would require the measurement of porphyrin levels in blood, urine, or tissues or the identification of UROS gene defects. 653 $aCATTLE 653 $aPINK TEETH 653 $aPORPHYRIN 653 $aUROPORPHYRIN 653 $aVETERINARY 653 $aZEBU 700 1 $aMACHADO, M. 700 1 $aBROMBERGER, C.R 700 1 $aOLIVEIRA-FILHO, J.P. 700 1 $aBORGES, A.S. 700 1 $aSOTO-BLANCO, B. 700 1 $aBORGES, J.R.J. 700 1 $aCÂMARA, A.C.L. 700 1 $aCASTRO, M.B.D. 773 $tFrontiers in Veterinary Science, 12 March 2021, Volume 8, Article number 632762. OPEN ACCESS. Doi: https://doi.org/10.3389/fvets.2021.632762
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INIA Tacuarembó (TBO) |
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
04/06/2018 |
Actualizado : |
04/06/2018 |
Tipo de producción científica : |
Documentos |
Autor : |
NIELL, S.; JESÚS, F.; GÉREZ, N.; SANTOS, E.; DÍAZ, R.; CESIO, V.; HEINZEN, H. |
Afiliación : |
S. NIELL, Universidad de la República (UdelaR)/ Centro Universitario Regional Noroeste, Salto (CENUR); F. JESÚS, Universidad de la República (UdelaR)/ Centro Universitario Regional Noroeste, Salto (CENUR); N. GÉREZ, Universidad de la República (UdelaR)/ Facultad de Química; E. SANTOS, Universidad de la República (UdelaR)/ Facultad de Ciencias; R. DÍAZ, MGAP/ DIGEGRA (Dirección General de la Granja, Ex-JUNAGRA); V. CESIO, Universidad de la República (UdelaR)/ Facultad de Química; H. HEINZEN, Universidad de la República (UdelaR)/ Facultad de Química. |
Título : |
Estudio de la distribución de residuos de agroquímicos en productos de la colmena y su relación con las zonas de producción apícola del país. |
Fecha de publicación : |
2018 |
Fuente / Imprenta : |
In: INIA (Instituto Nacional de Investigación Agropecuaria); Programa Nacional Producción Familiar. Nuevos retos de la apicultura para un ambiente en transformación. Jornada de divulgación. Las Brujas, Canelones (UY): INIA, 2018. |
Páginas : |
p. 10. |
Serie : |
(Serie Actividades de Difusión; 783) |
ISSN : |
1688-9258 |
Idioma : |
Español |
Thesagro : |
ABEJA MELIFERA; COLMENA. |
Asunto categoría : |
-- |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/9967/1/sad-783-Niell-et-al.-p.10.pdf
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Marc : |
LEADER 00902naa a2200241 a 4500 001 1058653 005 2018-06-04 008 2018 bl uuuu u00u1 u #d 022 $a1688-9258 100 1 $aNIELL, S. 245 $aEstudio de la distribución de residuos de agroquímicos en productos de la colmena y su relación con las zonas de producción apícola del país. 260 $c2018 300 $ap. 10. 490 $a(Serie Actividades de Difusión; 783) 650 $aABEJA MELIFERA 650 $aCOLMENA 700 1 $aJESÚS, F. 700 1 $aGÉREZ, N. 700 1 $aSANTOS, E. 700 1 $aDÍAZ, R. 700 1 $aCESIO, V. 700 1 $aHEINZEN, H. 773 $tIn: INIA (Instituto Nacional de Investigación Agropecuaria); Programa Nacional Producción Familiar. Nuevos retos de la apicultura para un ambiente en transformación. Jornada de divulgación. Las Brujas, Canelones (UY): INIA, 2018.
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